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Key takeaways Individuals with ulcerative colitis may face difficulties absorbing vitamin B12 due to intestinal inflammation, which can lead to a deficiency

We need much larger, more thorough trials to determine whether this peptide is safe or even effective to try

Reliable references such as a peer reviewed review published in the National Institutes of Health PubMed Central library on how NAD+ metabolism is regulated across aging and disease reinforce that supervised, evidence informed care is the safest path with any wellness therapy

However, persistently high serum B12 levels warrant medical investigation, as they may indicate liver disease, kidney dysfunction, or haematological disorders rather than simple overconsumption