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After induction of LTP, fEPSPs were recorded for 4 h

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58,59 Moreover, in 1971, Corey and Skoulos successfully synthesized prostaglandins, and during the 1970s, Brown and Goldstein discovered the low-density lipoprotein receptor pathway, which not only provides cells with the cholesterol necessary for constructing cell membranes and other biomolecules but also helps to maintain cholesterol homeostasis in the plasma

In the absence of activating stimuli, the stability of Hif1a is regulated by hydroxylase domain proteins (PHDs) and the von Hippel-Lindau tumor suppressor protein (VHL)