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It discusses the mechanisms underlying cardiovascular diseases resulting from copper excess and deficiency, particularly focusing on the pathogenic mechanisms related to oxidative stress and mitochondrial metabolism disorders

Unlike 5-Amino-1MQ, tesofensine doesn't alter intracellular metabolism

229 Clinical trials in postmenopausal women have found a 0.5% vaginal DHEA preparation providing 6.5 mg of DHEA per day or 50 mg of oral DHEA effectively reduced symptoms of genitourinary syndrome of menopause without stimulating the endometrium, and may reduce hot flashes and menopausal symptoms

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