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Both Cognizin and Setria have extensive human studies supporting their efficacy -- not just in vitro or animal models, but actual clinical trials with measurable outcomes

Glycosylation in cancer: mechanisms and clinical implications

10.3389/fonc.2015.00131 Front

Can Res 65:60296033 Yeh W-L, Lin H-Y, Huang C-Y, Huang B-R, Lin C, Lu D-Y, Wei K-C (2015) Migration-prone glioma cells show curcumin resistance associated with enhanced expression of miR-21 and invasion/anti-apoptosis-related proteins