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2017 Cell study used 5 mg/kg intraperitoneal injection three times per week in aged mice, with treatment periods of several weeks the three-times-weekly dosing suggests the peptide maintains sufficient functional concentrations for at least 48-72 hours per dose (PMID: 28340339)

When human amylin alanine at position 5 was mutated to serine (human calcitonin has serine as the corresponding residue to human amylin alanine at position 5), the mutation increased the potency of human amylin by 14-fold for CTR activation and by 9.1-fold for amylin receptor 3 activation

RBC glutathione was measured by Immunosciences Lab using a kit provided by Oxis Research (Foster City, CA)