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This was confirmed by using immunoblot analysis, with strongly decreased NBEAL2 levels 48h after transfection (Figure 6C)

Pathogens 12:746

In amyloid precursor protein Swedish mutation (APPSw) transgenic mice, dietary curcumin treatment dose-dependently decreased interleukin-1 beta (IL-1), oxidative stress markers, amyloid plaque accumulation, and microglial activation [220]