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The clinically dangerous fraction is "free" or non-ceruloplasmin-bound copper (NCC)

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USA 98 , 43794384 (2001)

International Journal of Pharmacology 20 (4), 672681 (2024) Brown, E., Rajeev, S.P., Cuthbertson, D.J., Wilding, J.P.: A review of the mechanism of action, metabolic profile and haemodynamic effects of sodium-glucose cotransporter2 inhibitors