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For these analyses, the UV kinetic method was applied using the Mindray BS-200 Chemistry Analyzer (Shenzhen, China), following the procedures outlined by the commercial kit from Bioclin Bioqumica (Belo Horizonte, Minas Gerais, Brazil)

Ethics statement The studies involving human participants were reviewed and approved by the Ethics Committee of Shanghai Municipal Hospital of Traditional Chinese Medicine

A higher dose of steroid may be needed at times of major stress, such as surgery or very extensive dental work or serious infection

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