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If you extrapolate the AOD 9604 rate linearly (which is generous, given that the OPTIONS study showed diminishing returns over time), you might expect roughly 8 to 10 kilograms over 18 months

Conclusion: In this single-site study, we found that HH was safe and effective for patients with cirrhosis and holds promise as a hepatology care delivery model

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In addition, in congenital morphea the disease duration until appropriate systemic treatment initiation was found to be even longer, i.e., up to 4 years, hence a greater risk for physical and cosmetic sequalae (27, 28)