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Los estudios realizados sobre cereales, leguminosas y forrajes indicaron un grado alarmante de infestacin de hongos

Nucleases may cause off-target effects on regions of the genome with similar homology to the site of interest or create mosaic animals where not all cells in the blastocyst were successfully edited by the injection of embryonic stem cells

Despite its hydrophobic nature, limited bioavailability and rapid metabolism are viewed as stumbling blocks that have hampered its therapeutic activity [26]

Moffatt BA, Stevens YY, Allen MS et al (2002) Adenosine kinase deficiency is associated with developmental abnormalities and reduced transmethylation