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Iafolla AK, Thompson Jr RJ, Roe CR (1994)

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showed that the use of combination pegylated IFN with ribavirin and a protease inhibitor seemed to be highly effective in treating HCV-related MC.20 Dermatologic manifestations of MC respond to the treatment and clearance of HCV.21 Patients who relapse after initial clearance of HCV usually have relapses in their vasculitis that parallel the return of viremia.20 In summary, treatment of HCV should not be deferred due to the presence of MC and vasculitis.22 Because of the involvement of HCV in the development of MC, treatment of HCV alone generally improves mild to moderate MC