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Current research implicates several interrelated pathogenic mechanisms, including persistent neuroinflammation, mitochondrial dysfunction [27], excessive production of reactive oxygen species (ROS) [28], reduced dopamine synthesis [8], impaired cerebral glucose metabolism [8], and the accumulation of misfolded -synuclein in the form of Lewy bodies [29]

To resolve this paradox, Jain et al

Following liver injury from various pathological factors, macrophages, T cells, and other inflammatory cells secrete numerous chemokines and inflammatory factors, instigating immune cell recruitment to the injury site

Famine, economic collapse and years of fighting have forced people out of South Sudan faster than from any other nation on the planet