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Melatonin as a stabilizer of mitochondrial function: role in diseases and aging

doi:10.1080/01635581.2019.1637006 15

This pocket is formed by residues in transmembrane helices 1 (TM1), 2 (TM2), 3 (TM3), and 7 (TM7), along with contributions from extracellular loop 2 (ECL2)

By integrating high-resolution bio-imaging with data-driven biochemistry, they synthesize light-activated compounds that catalyze specific biological responses for enhanced therapeutic outcomes