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A distinction is made between two nocturnal blood pressure profiles: o reduced dipping, characterized by an average nocturnal BP reduction 18 points has been validated as indicative of a sleep disturbance and warranting an additional diagnostic work-up with vPSG [151]

264,265 Chronic hyperglycemia elevates ROS production through multiple pathways, including enhanced glucose oxidation, activation of NADPH oxidases, and dysfunction of the mitochondrial electron transport chain

Drug design challenges Several issues must be addressed concerning the development of an efficacious drug to treat AD: (1) the drug must penetrate the BBB to influence damaged neurons in memory-associated brain structures

Like many medical practices around the country, his GP clinic, in a small north-east Tasmanian fishing town, still relies on antiquated fax services to send pathology forms and scripts