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Drug Des Dev Ther 2021;15:320721

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[7] Mitochondrial pyruvate carriers In cells with mitochondria, most of the pyruvate produced in the cytosol enters the mitochondrial matrix passing through the outer and the inner mitochondrial membranes

Key strategies: Simultaneous production (saying words together- check out this free DTTC hierarchy available in English and Spanish) Multisensory cueing (visual, tactile, auditory) High repetitions in play-based or child-led sessions Respecting autonomy and providing neurodiversity-affirming care When AAC Is Needed AAC (Augmentative and Alternative Communication) can and should be used alongside verbal therapy, especially when speech is inconsistent or unintelligible