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As mentioned above, mutation of the latter residues leads to a pronounced lowering of the MGST1 activity and mutation of the former leads to an activity decrease as well as a 67 fold increase in K m for GSH (Table 1)

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doi: 10.1016/j.micinf.2008.08.004 205 OddyWHHicklingSSmithMAOSullivanTARobinsonMde KlerkNHet al

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