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doi: 10.1016/j.cell.2011.02.013 46 NunesSCRamosCSantosIMendesCSilvaFVicenteJBet al

Lung cancer: epidemiology and screening

Under these circumstances a thiyl radical is formed that will initiate and propagate an oxygen-dependent chain reaction, involving peroxyl radical formation that will lead to further consumption of intracellular GSH (Quijano et al., 1997)

The peptide upregulates genes involved in collagen synthesis, including COL1A1 (Type I collagen), COL3A1 (Type III collagen), and COL4A1 (Type IV collagen)