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Tirzepatide AOD-9604 AOD-9604 (Advanced Obesity Drug) is a modified fragment of human growth hormone (amino acids 177-191)

doi: 10.1038/s41598-019-50965-9 44 CastriotaFRieswijkLDahlbergSla MerrillMASteinmausCSmithMTet al

In addition, drug-tolerant persister cells are highly dependent on GPx4 for survival, and loss of GPx4 function contributes to ferroptotic cell death and prevents drug resistance, suggesting a novel therapeutic avenue in cancers [12]