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Description

Chinese Medical Journal Pulmonary and Critical Care Medicine

Evidence suggests that solute carrier family 25 member 10 (SLC25A10) mediates the import of cytosolic GSH into mitochondria to prevent iron deposition-induced myocardial ferroptosis, a process regulated by the Nrf2/MPV17 axis, which also restores mitochondrial respiratory chain activity and may exert beneficial effects on cardiac function in MIRI [144]

Cheng K, Ashby D, Smyth RL

First, 3-phosphoglycerate is oxidized to 3-phosphohydroxypyruvate with concomitant production of NADH, catalyzed by phosphoglycerate dehydrogenase (PHGDH)