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These changes can result in a reduction of the amount of capillaries that supply the heart with blood, as well as fibrosis, chemical changes, and changes in the metabolism and organization of heart cells

+ T cells, activated T cells and memory T cells (Norris et al., 1998)

Overall, this work provided a cascade-enhanced nanocatalytic strategy against hypoxic tumor by integrating respiration inhibition, GSH depletion and targeted delivery for effective starving-chemodynamic therapy