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Mitochondria: Cell structures where energy is produced

Importantly, although patient perceptions of deformity may not predict objective measures of deformity, and patient distress is poorly correlated with objective measures of deformity (Hellstrom 2013), patient perceptions of deformity correlate with distress

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By inhibiting PDK, DCA facilitates PDH-mediated conversion of pyruvate to acetyl-CoA, thus enhancing mitochondrial oxidative capacity and reducing lactate buildup [142]