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Description

In biomedicine, the transition metal copper has a Janus-faced dual role, as an essential but static cofactor of vital enzymes but also as a highly detrimental poison, if in excess

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Loss of PMK-1 (transcription factor of p38 MAPK) compromises the extended lifespan of daf-2(e1370) (insulin/insulin-like growth factor (IGF) receptor longevity mutant) 45