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Another study involving 28 CDLBP patients compared the clinical outcomes of IRFT (13 patients) to a placebo treatment (15 patients) and found that IRFT was not effective in reducing CDLBP (Barendse et al., 2001)

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Future research including potential clinical and preclinical trials, mechanistic studies, and exploration of different vitamin and mineral supplement studies are required to uncover the complete potential of antioxidant supplements for cancer treatment or determine their safety and effectiveness when used alongside standard cancer treatments