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This suppression cascaded to reduce denitrification enzyme activity, with declines in nirK and nirS gene abundances, alongside marked shifts in bacterial community structure, even at the lowest realistic NP concentration (Simonin et al., 2016)

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However, in some tumors, such as pancreatic cancer and melanoma, additional glutamine can inhibit the proliferation of tumor cells, and this mechanism is closely related to the regulation of the immune microenvironment

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