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Histamine b

Figure 1 Regulatory mechanism (Figure 1): The essence of ferroptosis lies in the depletion of glutathione (GSH) and the decline in the activity of glutathione peroxidase (GPX4), which leads to a reduction in the amount of glutathione reductase catalyzed by GPX4 and excessive accumulation of lipid peroxides (10)

Baseline inflammation, as observed in advanced liver fibrosis or concomitant infections, impairs AAV intracellular trafficking and nuclear entry through altered endosomal processing and cytosolic innate immune sensing [12, 205]

Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways