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To further assess the effect of APAP treatment on infected organs, histological analyses were performed on spleens, lungs and brains

When COMT activity is low, competitive oxidation of catechol estrogens to semiquinones and then to quinones, catalyzed by CYP or peroxidases, can occur (Figure 2)

Peer review Peer review information Nature Communications thanks Ching-Ping Tseng and the other anonymous reviewer(s) for their contribution to the peer review of this work