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Medications that can harm the kidneys like nonsteroidal anti-inflammatory drugs and certain types of antibiotics should be avoided by all people with kidney disease

In fact, NRF2 activation as a clinical target is well established for the treatment of MS since the potent NRF2-activator dimethyl fumarate (DMF) was approved by FDA as first disease-modifying agent in 2013 (Fox et al., 2012