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The oxidative degradation mechanism is depicted in Figure 3C, where H 2 O 2 triggers the breakdown of GO@GSH-FA by detaching the phenylboronic acid derivative, leading to the accelerated release of the GSH

The 20.9% mean body weight reduction seen in SURMOUNT-1 at 72 weeks reflects tirzepatides direct receptor binding and metabolic effects, not secondary antioxidant support

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