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Topical dihydrotestosterone to treat micropenis secondary to partial androgen insensitivity syndrome (PAIS) before, during, and after puberty A case series

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Lignans from flaxseed, converted to enterolactone (EL) and enterodiol by gut microflora within the intestines, possess weak estrogenic activity that competes with endogenous oestrogens for ER binding causing decreased mitogenic stimulation and lower circulating estrogen concentrations via upregulation of sex hormonebinding globulin (SHBG) (189, 190)

However, the source paper contains inconsistent descriptions of the SPR concentration rangethe figure legend specifies 23.4496,000 nM, whereas the methods section lists 1.8931.25 nM, a discrepancy of several thousand-fold