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doi: 10.1186/s13098-019-0497-8 101 VorugantiVSCaiGKloheDMJordanKCLaneMAFreeland-GravesJH

The following inhibitors were injected: oligomycin (2 M), FCCP (2 M), rotenone and antimycin A (1 M)

Published binding assays show PT-141's Ki for MC4R is approximately 0.9 nM, compared to 12 nM for MC1R, meaning it activates sexual arousal pathways at doses far below the threshold for melanogenesis

Interactions of the choroid, Bruch's membrane, retinal pigment epithelium, and neurosensory retina collaborate to form the outer blood-retinal-barrier