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Binding data were adjusted to a zero sample and the reference flow cell values subtracted before the Langmuir 1:1 ligand binding model (BIAevaluation software) were used to determine binding kinetics

doi:10.1016/j.jlr.2021.100023 52

Improved circulation may, in turn, speed up the recovery process and support overall tissue health

To put that in perspective, you'd need massive amounts of oral supplements to come close to these therapeutic doses - and most wouldn't make it to your cells intact