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The subacute MPTP model is generated by administering MPTP once daily over five consecutive days, whereas an acute model is induced by delivering MPTP every two hours for four times in only one day (202)

This is an important finding with regard to PD pathology, as mature neurons depend on cholesterol synthesized and exported from astrocytes (Poirier et al., 1993

The acute effects of dopamine and noradrenaline reuptake inhibition on energy homeostasis demonstrated their additive effects on short-term food intake (53)