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Many people notice sleep improvements first, followed by changes in energy, recovery, and body composition over several weeks or months

[DOI] [PubMed] [Google Scholar] 107.Pourhadi M, Jamalzade F, Jahanian-Najafabadi A, Shafiee F

47 The difference was particularly significant in the high dose group, suggesting an in vivo antioxidant effect

In the treatment portion of this guideline, most statements are Options because most treatments demonstrate limited efficacy in a subset of patients that is not readily identifiable a priori