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Ethics statement The animal study was approved by Changzhi Medical College's Experimental Animal Care & Use Committee

Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were assayed according to Reitman and Frankel

Safety Handling: This is a professional-grade cosmetic active ingredient intended for industrial production and laboratory research use only

While I dont believe that laughter is necessarily the best medicine (my patients would forcefully object if I wrote a script for laughter instead of Vicodin), personal interactions involving humor, levity, and sincere interest are extremely important for our patients well-being