interaction of chloroacetamide electrophiles with cellular glutathion Selective covalent targeting GPX4 using masked nitrile-oxide Discovery of novel benzylaniline derivatives
Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Glutathione dynamics in subcellular compartments and implications for drug development ScienceDirect Delineating cysteine reactive compound modulation of cellular proteostasis processes Nature Chemical Biology
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