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( We are inviting public comments on whether NexoBrid TM meets the cost criterion

This is consistent with storage guidelines for all injectable peptides

If the NDCs within a billing and payment code have a mix of missing ASP units, negative ASP units, and/or zero ASP units, CMS will apportion a $0 rebate amount to each NDC with missing units that are not sold or marketed during the applicable calendar quarter, each NDC with negative units, and each NDC with units equal to zero, and CMS will equally apportion a positive rebate amount to NDCs with missing units that were sold or marketed during the applicable quarter by dividing the total rebate amount for the grouped billing and payment code by the total number of such NDCs within the billing and payment code

These effects are dose-dependent and transient, typically returning to baseline within 1-2 hours