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Aging can be defined as a progressive and irreversible decline in physiological integrity, driven by the accumulation of stressor-mediated damage and subsequent dysfunction at the cellular, tissue, and organ level [4]

As a single, well-characterised compound, it has a defined molecular structure, molecular weight, and an established position in copper-peptide research literature, where it has been studied for its metal-binding and copper-chelating properties

The identified chicken sequences were filtered out and excluded from the following analyses

It is important to note that S1P is considered a tumor-promoting lipid due to its impact on autophagy, and increased S1P levels have been identified as a drug-resistance mechanism in some cancer types