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Conclusion: CTSD may be a possible biomarker of severe NAFLD since its hepatic/adipose tissue expression as well as circulating levels correlated with liver damage thus allowing to discriminate advanced disease

Similarly, metabolomic profiling of blood and CSF in patients, alongside microbiome data, can identify which microbial metabolites truly cross into the brain and affect pathways like amyloid deposition or axonal integrity

Vegetables in the brassica family produce the most glutathione, but the molecule is present in large amounts in several other vegetables

The Zr released from Mn-MOF downregulated GSH efficiently (Figure 5G), thus elevating Mn-MOF-induced ROS concentration, leading to the deactivation of GPX4 and ROS-enhanced ferroptosis