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170,185 In a mouse model of mesothelioma tumor, the use of trientine, d-penicillamine, and TTM could also exhibit inhibitory effects on tumor growth and impede tumor angiogenesis

Aside from wound healing, TGF- plays a significant role in immunomodulation by promoting the expansion of Treg cells, inhibiting T cells, B cells, and NK cells, and polarises pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages (Figure 3B

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