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Critical roles in maintaining redox are exerted by antioxidant systems, including the thioredoxin/peroxiredoxin systems and the nuclear erythroid related transcription factor 2 (Nrf2), which regulates the expression of detoxification proteins such as Kelch-like ECH-associated protein 1 (Keap1) [181]

Nelson JE, Klintworth H, Kowdley KV (2012) Iron metabolism in nonalcoholic fatty liver disease

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The frequency with this bacterium is high in developing countries and poor socio-economic conditions, so that people living in these conditions are generally at high risk for re-infection