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A comprehensive summary of CHAC1 expression across tumor types, along with TP53 status and ferroptosis susceptibility, is provided in Supplementary Table S1

Glaucoma Mechanism: Progressive optic nerve damage from elevated intraocular pressure, vascular insufficiency, or neurodegeneration

Multiple signaling pathways intersect and collaborate to govern the interconnected processes of mitochondrial energetics, biogenesis, ROS production, preservation and repair of mitochondrial DNA (mtDNA), and mitophagy (115)