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Renner S, Braun-Reichhart C, Blutke A, Herbach N, Emrich D, Streckel E, Wnsch A, Kessler B, Kurome M, Bhr A, Klymiuk N, Krebs S, Puk O, Nagashima H, Graw J, Blum H, Wanke R, Wolf E (2013) Permanent neonatal diabetes in INS(C94Y) transgenic pigs

Thus, the stage is set for a vicious cycle wherein organelle-driven ferroptosis and immune cell-mediated inflammation mutually reinforce each other, driving COPD progression