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Increased Expression of System Xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance

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Standardize SCFAssampling sites and quantitative platforms (reporting feces/cecum/serum separately) and supplement with blood/tissue exposure data to avoid the implicit leap that fecal content systemic exposure. Use longitudinal time sampling (early/mid-term/late stage) to see whether the changes of SCFAs preced inflammation remission, so as to reduce the misunderstanding of causal inversion

Feelisch, M