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Dyspnea is the most common presenting symptom, often prompting initial medical consultation, while chronic dry cough and velcro-like crackles on auscultation are also characteristic clinical features [1, 2]

It is present in every cell of the body, where it provides potent antioxidant protection, supports detoxification, and modulates the immune system

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Data presented here demonstrate that LPS-induced reversible oxidation within PDC occurs in PDCE2 in both THP-1 cells and primary human monocytes