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[4] [6] In clinical contexts, high-dose intravenous ascorbic acid may modulate immune function, enhance wound healing, and support endothelial integrity

Mutants of these genes have altered trichime elongation and growth direction

These immune responses, including the release of pro-inflammatory cytokines (e.g., TNF-, IL-1), can signal to the brain via the vagus nerve and the systemic circulation (Ma et al., 2020)