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296,297,298 Typically, NF-B binds to its inhibitor IB in the cytoplasm

At the same time, reduced IDO activity reduced kynurenine and further weakened peripheral immune tolerance, which played a driving role in the hypothyroidism immune disorder caused by the imbalance of the whole gut microbiota (Clarke et al., 2017)

Healthy Aging: Reduces the impact of environmental stressors

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