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During rapid inflammatory responses, the immune system acts as a sensory system, receiving signals and transmitting them to the brain via humoral pathways (e.g., the cytokine IL-1 stimulates nerve cells to uptake glucose, supporting central nervous system metabolism) or neural pathways to trigger physiological reactions (105)

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Combining GH and IGF-1 can produce additive or synergistic effects on muscle hypertrophy and recovery by engaging parallel anabolic signaling pathways. Liu, J.P., Endocrine Reviews This stack is popular during: Recomposition or lean bulking phases Post-injury recovery Contest prep when retaining mass while cutting Other Common Stack Combinations IGF-1 LR3 + Insulin (Advanced Use Only) This stack maximizes nutrient shuttling and glycogen supercompensation but poses serious hypoglycemia risks