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Description

In a double-blinded randomized controlled trial, overweight women with PCOS who were resistant to clomiphene (an FDA-approved drug used to treat infertility) were given either metformin (a drug used to treat high blood sugar and/or diabetes) and L-carnitine or just metformin alone

TEM revealed that Sertoli cells were slightly detached from the seminiferous epithelium, where the cell membrane and nuclear membrane structure were still clear