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However, when they increase in number or become more concentrated in a particular area, they can cause annoyance or discomfort

When an action potential reaches the presynaptic terminal, Ca 2+ influx via voltage-gated calcium channels (VGCC) triggers the fusion of vesicles loaded with neurotransmitter with the cell membrane, thereby releasing neurotransmitter in the synaptic cleft (Nishimune et al., 2016

Composition of the urinary microbiome has been found to be altered in urinary disorders, including IC/BPS

All procedures performed in this study involving human participants were in accordance with the Declaration of Helsinki (as revised in 2013)