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doi: 10.1186/s12885-021-08541-w 25 ChenH-XWuY-PLiWShenH-HChenZ-H

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In patients with diabetes mellitus, the incidence of GI symptoms is significantly higher than in those without diabetes, especially in women with poor glycemic control, long-standing diabetes, or other diabetic complications, although the reported prevalence of DGE varies widely by region (Krishnasamy and Abell, 2018), with dysphagia (63%), gastroesophageal reflux (41%), early satiety or nausea (10%20%), constipation (60%), and diarrhea (20%) being especially prominent (Revicki et al., 2003